XBI vs VOO: Complete Comparison
SPDR S&P Biotech ETF vs Vanguard S&P 500 ETF โ overlap, correlation, performance & risk analysis
Visual Overlap
Price Performance
Historical price comparison over 3M
๐Performance Comparison
โ ๏ธRisk Metrics
Interpretation:
- ๐ Lower volatility = smoother ride
- โก Higher Sharpe/Sortino = better risk-adjusted returns
- โ ๏ธ Smaller max drawdown = less worst-case pain
- ๐ Beta > 1 = more volatile than S&P 500
โ๏ธHead-to-Head Comparison
๐ VOO wins this comparison
Key Factors
โถAdditional Metrics (5)
Bottom line: VOO wins with better expense ratio and number of holdings and 5-year return. Consider VOO for your portfolio, but XBI is still a solid choice if you prefer its specific advantages.
Detailed Overlap Analysis
4 shared holdings representing 0.5% portfolio overlap
Top Shared Holdings
| # | Stock | XBI Weight | VOO Weight | Overlap |
|---|---|---|---|---|
| 1 | VRTX VRTX | 1.24% | 0.19% | 0.19% |
| 2 | REGN REGN | 1.29% | 0.14% | 0.14% |
| 3 | INCY INCY | 1.26% | 0.03% | 0.03% |
| 4 | MRNA MRNA | 1.34% | 0.02% | 0.02% |
Overlap by Sector
Showing top 5 sectors by overlap contribution
Top Holdings Only in XBI
Unique to XBI
| Symbol | Name | Weight |
|---|---|---|
| FOLD | FOLD | 1.44% |
| TVTX | TVTX | 1.40% |
| EXEL | EXEL | 1.35% |
| BMRN | BMRN | 1.34% |
| ROIV | ROIV | 1.33% |
Top Holdings Only in VOO
Unique to VOO
| Symbol | Name | Weight |
|---|---|---|
| NVDA | NVDA | 7.37% |
| AAPL | AAPL | 7.07% |
| MSFT | MSFT | 6.24% |
| AMZN | AMZN | 3.86% |
| AVGO | AVGO | 3.24% |
Price Correlation
How We Calculate Overlap
We use the minimum weight method with normalization to calculate portfolio overlap:
Overlap = ฮฃ min(weightA, weightB) for each shared holdingNormalization: Holdings weights are normalized to sum to 100% before comparison. This ensures accurate overlap calculations even when analyzing partial holdings data (e.g., top 50 positions).
Conservative approach: We consider only the smaller allocation for each shared position, giving you a realistic view of true portfolio overlap.
๐ This analysis is based on publicly available holdings data. For the most current and complete holdings information, please visit the official ETF provider websites.
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